I-Chlorothiazide

Inkcazelo emfutshane:

Igama le-API Isalathiso Inkcazo USDMF EU DMF CEP
I-Chlorothiazide I-Diuretics USP/EP      


Iinkcukacha zeMveliso

Iithegi zeMveliso

IINKCUKACHA ZEMVELISO

Imvelaphi

I-Chlorothiazide yi-inhibitor ye-carbonic anhydrase kwaye ingaphantsi kancinci ngamandla kune-acetazolamide.Le ngqungquthela ibonakaliswe ukuvimba ukubuyiswa kwakhona kwe-sodium kunye ne-chloride ion.

Inkcazo

I-Chlorothiazide yi-diuretic kunye ne-antihypertensive.(IC50=3.8 mM) Ithagethi: Okunye I-Chlorothiazide sodium (Diuril) sisichaphazi-manzi esisetyenziswa ngaphakathi kwesibhedlele okanye kusetyenziso lomntu siqu ukulawula ulwelo olugqithisileyo oluyanyaniswa nokungaphumeleli kwentliziyo.Ikwasetyenziswa njenge-antihypertensive.Uninzi ludla ngokuthathwa njengepilisi, ludla ngokuthathwa ngomlomo kanye okanye kabini ngemini.Kwimeko ye-ICU, i-chlorothiazide inikwa i-diurese isigulane ngaphezu kwe-furosemide (Lasix).Ukusebenza ngendlela eyahlukileyo kune-furosemide, kwaye ifunnwe ngokungena kwi-enterate njenge-suspension ehlaziyiweyo elawulwa ityhubhu ye-nasogastric (i-tube ye-NG), la mayeza mabini anamandla omnye komnye.

Ulingo lwezonyango

Inombolo ye-NCT Umxhasi Imeko Umhla wokuqala

Isigaba

NCT03574857 IYunivesithi yaseVirginia Ukungaphumeleli kwentliziyo NgoJuni 2018

Inqanaba lesi-4

NCT02546583 IYunivesithi yaseYale|Intliziyo yeSizwe, iLung, kunye neZiko leGazi (NHLBI) Ukumelwa yintliziyo EyeThupha 2015

Ayingeni

NCT02606253 IYunivesithi yaseVanderbilt | Iziko lezoNyango leYunivesithi yaseVanderbilt Ukumelwa yintliziyo NgoFebruwari 2016

Inqanaba lesi-4

NCT00004360 Iziko leSizwe leZibonelelo zoPhando (NCRR)|Dyunivesithi yaseMntla-ntshona|Ofisi yeZifo eziNqabileyo (ORD) Isifo sikashukela i-Insipidus, iNephrogenic NgoSeptemba 1995

NCT00000484 Iziko leSizwe leNtliziyo, imiphunga, kunye neGazi (NHLBI) Izifo zentliziyo | Izifo zentliziyo | Uxinzelelo | Izifo zeVascular Epreli 1966

Inqanaba lesi-3

Ubume beMichiza

Chlorothiazide

ISIQINISEKISO

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

ULAWULO LOMgangatho

Quality management1

Isindululo18Iiprojekthi zoVavanyo loBulunga ezivunyiweyo4, kwaye6iiprojekthi ziphantsi kolwamkelo.

Quality management2

Inkqubo yolawulo lomgangatho wehlabathi ephucukileyo ibeke isiseko esiluqilima sokuthengisa.

Quality management3

Ukongamela umgangatho kutyhutyha umjikelo wobomi bemveliso ukuqinisekisa umgangatho kunye nesiphumo sonyango.

Quality management4

Iqela leMicimbi yoLawulo lobuGcisa lixhasa iimfuno zomgangatho ngexesha lesicelo nokubhaliswa.

ULAWULO LWEMVELISO

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