Captopril

Inkcazelo emfutshane:

Igama le-API Isalathiso Inkcazo USDMF EU DMF CEP
Captopril Uxinzelelo lwegazi USP/EP  


Iinkcukacha zeMveliso

Iithegi zeMveliso

IINKCUKACHA ZEMVELISO

Inkcazo

I-Captopril (SQ-14534) inamandla, inhibitor ekhuphisanayo ye-angiotensin-converting enzyme (ACE).

I-In vitro

I-Captopril (i-SQ-14534) ibonakaliswe ukuba inobungozi obufanayo kunye neenzuzo zokufa kulabo be-diuretics kunye ne-beta-blockers kwizigulane ezixinzelelekileyo.I-Captopril (i-SQ-14534) ibonakaliswe ukulibazisa ukuqhubela phambili kwe-nephropathy yesifo seswekile, kwaye i-enalapril kunye ne-lisinopril zithintela ukuphuhliswa kwe-nephropathy kwizigulane ze-normoalbuminuric ezinesifo seswekile[1].Umlinganiselo olinganayo we-cis kunye ne-trans States ye-Captopril (SQ-14534) ikhona kwisisombululo kwaye i-enzyme ikhetha kuphela i-trans state ye-inhibitor ebonisa ukuhambelana kwe-architectural kunye ne-stereoelectronic kunye ne-substrate ebophelelayo i-groove [2].

I-MCE ayizange iqinisekise ngokuzimeleyo ukuchaneka kwezi ndlela.Zenzelwe ireferensi kuphela.

Ulingo lwezonyango

Inombolo ye-NCT Umxhasi Imeko Umhla wokuqala

Isigaba

NCT03179163 IYunivesithi yasePenn State|Intliziyo yeSizwe, iLung, kunye neZiko leGazi (NHLBI) Uxinzelelo lwegazi, kubalulekile NgoJulayi 20, 2016

Isigaba 1|Isigaba 2

NCT03660293 IYunivesithi yaseTanta Isifo seswekile, uhlobo loku-1 Ngomhla woku-1 kuTshazimpuzi, ngo-2017

Ayingeni

NCT03147092 Centro Neurológico de Pesquisa e Reabiitação, eBrazil Uxinzelelo lwegazi | Uxinzelelo lwegazi NgoFebruwari 1, 2018

Isigaba sokuqala soku-1

NCT00252317 IRigshospitalet, eDenmark I-Aortic Stenosis Novemba 2005

Inqanaba lesi-4

NCT02217852 Isibhedlele sase-West China Uxinzelelo lwegazi Agasti 2014

Inqanaba lesi-4

NCT01626469 Brigham kunye neSibhedlele sabaseTyhini Uhlobo lwesi-2 seswekile iMellitus Meyi 2012

Isigaba 1|Isigaba 2

NCT00391846 AstraZeneca Ukungaphumeleli kwentliziyo|Ukungasebenzi kakuhle kwe-Venticular, eKhohlo Okthobha 2006

Inqanaba lesi-4

NCT00240656 IYunivesithi yezoNyango yaseHebei Uxinzelelo lwegazi, imiphunga Okthobha 2005

Inqanaba loku-1

NCT00086723 IYunivesithi yaseNorthwestern|Iziko leSizwe loMhlaza (NCI) Ithumba eliqinileyo labadala elingachazwanga, iProtocol ecacileyo Julayi 2003

Isigaba 1|Isigaba 2

NCT00663949 IYunivesithi yaseShiraz yeSayensi yezoNyango Isifo seswekile seNephropathy NgoFebruwari 2006

Isigaba 2|Isigaba 3

NCT01437371 Isibhedlele saseYunivesithi, eClermont-Ferrand|Servier|LivaNova Ukumelwa yintliziyo Agasti 2011

Inqanaba lesi-3

NCT04288700 KwiYunivesithi yaseAin Shams Infantile Hemangioma Nge-1 kaOkthobha, 2019

Inqanaba lesi-4

NCT00223717 IYunivesithi yaseVanderbilt | Iziko lezoNyango leYunivesithi yaseVanderbilt Uxinzelelo lwegazi NgoJanuwari 2001

Inqanaba loku-1

NCT02770378 IYunivesithi yase-Ulm|Unyango oluthembekileyo loMhlaza | Ingxowa-mali ye-Anticancer, eBelgium IGlioblastoma EyeNkanga 2016

Isigaba 1|Isigaba 2

NCT01761916 Instituto Materno Infantil Prof. Fernando Figueira I-Preeclampsia NgoJanuwari 2013

Inqanaba lesi-4

NCT01545479 Instituto de Cardiologia do Rio Grande do Sul Isifo sezintso NgoJanuwari 2010

Inqanaba lesi-4

NCT00935805 Hospital de Clinicas de Porto Alegre|Conselho Nacional de Desenvolvimento Científico e Tecnológico|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil Isifo seswekile | Uxinzelelo lwegazi Julayi 2006

NCT00742040 Isibhedlele sabantwana abagulayo Isifo sentliziyo Agasti 2008

Inqanaba lesi-2

NCT03613506 IYunivesithi yaseWuhan I-Radiotherapy Side Effect|Ukuthatha iCaptopril Ngo-Oktobha 25, 2018

Inqanaba lesi-2

NCT00004230 IYunivesithi yaseNorthwestern|Iziko leSizwe loMhlaza (NCI) Umhlaza Okthobha 1999

Inqanaba lesi-3

NCT00660309 Novartis Uhlobo lwesi-2 seswekile iMellitus Epreli 2008

Inqanaba lesi-4

NCT00292162 I-NHS Greater Glasgow kunye neClyde Ukungaphumeleli kweNtliziyo okuNgapheliyo | UFibrillation yeAtrial NgoJanuwari 2007

Ayingeni

NCT01271478 Coordinación de Investigación en Salud, Mexico Ukukrala|Isigaba sokuphela-Isifo sezintso Agasti 2009

Inqanaba lesi-4

NCT04193137 IYunivesithi yezoNyango yaseChongqing I-Aldosteronism yokuqala NgoNovemba 30, 2019

NCT00155064 Isibhedlele seYunivesithi yeSizwe yaseTaiwan Hyperaldosteronism Julayi 2002

Inqanaba lesi-4

NCT01292694 IYunivesithi yaseVanderbilt | Iziko lezoNyango leYunivesithi yaseVanderbilt Uxinzelelo lwegazi | Ukungaphumeleli okuNgenene okuZimelayo|IAtrophy yeeNkqubo ezininzi Matshi 2011

Inqanaba loku-1

NCT00917345 Isibhedlele seYunivesithi yeSizwe yaseTaiwan|Novartis I-Aldosteronism yokuqala NgoJanuwari 2008

NCT00077064 IQela loNyango lweRadiation Oncology|Iziko leSizwe loMhlaza (NCI)|NRG Oncology Umhlaza wemiphunga|Iingxaki zemiphunga|iRadiation Fibrosis NgoJuni 2003

Inqanaba lesi-2

Ugcino

Umgubo

-20°C

Iminyaka emi-3
 

4°C

iminyaka eyi-2
Kwi-solvent

-80°C

Iinyanga ezi-6
 

-20°C

Inyanga eyi-1

Ubume beMichiza

Captopril

ISIQINISEKISO

2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

ULAWULO LOMgangatho

Quality management1

Isindululo18Iiprojekthi zoVavanyo loBulunga ezivunyiweyo4, kwaye6iiprojekthi ziphantsi kolwamkelo.

Quality management2

Inkqubo yolawulo lomgangatho wehlabathi ephucukileyo ibeke isiseko esiluqilima sokuthengisa.

Quality management3

Ukongamela umgangatho kutyhutyha umjikelo wobomi bemveliso ukuqinisekisa umgangatho kunye nesiphumo sonyango.

Quality management4

Iqela leMicimbi yoLawulo lobuGcisa lixhasa iimfuno zomgangatho ngexesha lesicelo nokubhaliswa.

ULAWULO LWEMVELISO

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Umatshini wokuQinisa iFette waseJamani

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Japan Viswill Tablet Detector

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