China Chlorothiazide abavelisi kunye nababoneleli |CPF

I-Chlorothiazide

Inkcazelo emfutshane:

Igama le-API	Isalathiso	Inkcazo	USDMF	EU DMF	CEP
I-Chlorothiazide	I-Diuretics	USP/EP

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

IINKCUKACHA ZEMVELISO

Imvelaphi

I-Chlorothiazide yi-inhibitor ye-carbonic anhydrase kwaye ingaphantsi kancinci ngamandla kune-acetazolamide.Le ngqungquthela ibonakaliswe ukuvimba ukubuyiswa kwakhona kwe-sodium kunye ne-chloride ion.

Inkcazo

I-Chlorothiazide yi-diuretic kunye ne-antihypertensive.(IC50=3.8 mM) Ithagethi: Okunye I-Chlorothiazide sodium (Diuril) sisichaphazi-manzi esisetyenziswa ngaphakathi kwesibhedlele okanye kusetyenziso lomntu siqu ukulawula ulwelo olugqithisileyo oluyanyaniswa nokungaphumeleli kwentliziyo.Ikwasetyenziswa njenge-antihypertensive.Uninzi ludla ngokuthathwa njengepilisi, ludla ngokuthathwa ngomlomo kanye okanye kabini ngemini.Kwimeko ye-ICU, i-chlorothiazide inikwa i-diurese isigulane ngaphezu kwe-furosemide (Lasix).Ukusebenza ngendlela eyahlukileyo kune-furosemide, kwaye ifunnwe ngokungena kwi-enterate njenge-suspension ehlaziyiweyo elawulwa ityhubhu ye-nasogastric (i-tube ye-NG), la mayeza mabini anamandla omnye komnye.

Ulingo lwezonyango

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NCT02546583	IYunivesithi yaseYale\|Intliziyo yeSizwe, iLung, kunye neZiko leGazi (NHLBI)	Ukumelwa yintliziyo	EyeThupha 2015	Ayingeni
NCT02606253	IYunivesithi yaseVanderbilt \| Iziko lezoNyango leYunivesithi yaseVanderbilt	Ukumelwa yintliziyo	NgoFebruwari 2016	Inqanaba lesi-4
NCT00004360	Iziko leSizwe leZibonelelo zoPhando (NCRR)\|Dyunivesithi yaseMntla-ntshona\|Ofisi yeZifo eziNqabileyo (ORD)	Isifo sikashukela i-Insipidus, iNephrogenic	NgoSeptemba 1995
NCT00000484	Iziko leSizwe leNtliziyo, imiphunga, kunye neGazi (NHLBI)	Izifo zentliziyo \| Izifo zentliziyo \| Uxinzelelo \| Izifo zeVascular	Epreli 1966	Inqanaba lesi-3