China Chlorothiazide abavelisi kunye nababoneleli

Chlorothiazide

Inkcazelo emfutshane:

Igama le-API	Isalathiso	Inkcazo	I-USDMF	EU DMF	CEP
Chlorothiazide	I-Diuretics	USP/EP

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

IINKCUKACHA ZEMVELISO

Imvelaphi

I-Chlorothiazide yi-inhibitor ye-carbonic anhydrase kwaye ingaphantsi kancinci kune-acetazolamide. Le ngqungquthela ibonakaliswe ukuvimba ukubuyiswa kwakhona kwe-sodium kunye ne-chloride ion.

Inkcazo

I-Chlorothiazide yi-diuretic kunye ne-antihypertensive. (IC50=3.8 mM) Ithagethi: Okunye I-Chlorothiazide sodium (Diuril) sisichaphazi-manzi esisetyenziswa ngaphakathi kwesibhedlele okanye kusetyenziso lomntu siqu ukulawula ulwelo olugqithisileyo oluyanyaniswa nokungaphumeleli kwentliziyo. Ikwasetyenziswa njenge-antihypertensive. Idla ngokuthathwa njengepilisi, idla ngokuthathwa ngomlomo kanye okanye kabini ngemini. Kwimeko ye-ICU, i-chlorothiazide inikwa i-diurese isigulane ngaphezu kwe-furosemide (Lasix). Ukusebenza ngendlela eyahlukileyo kune-furosemide, kwaye ifunnwe nge-enterate njenge-suspension ehlaziyiweyo elawulwa ityhubhu ye-nasogastric (i-tube ye-NG), la mayeza mabini anamandla omnye komnye.

Ulingo lwezonyango

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NCT02606253	IYunivesithi yaseVanderbilt \| Iziko lezoNyango leYunivesithi yaseVanderbilt	Ukumelwa yintliziyo	NgoFebruwari 2016	Inqanaba lesi-4
NCT00004360	Iziko leSizwe leZibonelelo zoPhando (NCRR)\|Dyunivesithi yaseMntla-ntshona\|Ofisi yeZifo eziNqabileyo (ORD)	Isifo sikashukela i-Insipidus, iNephrogenic	NgoSeptemba 1995
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