China Captopril abavelisi kunye nababoneleli |CPF

Captopril

Inkcazelo emfutshane:

Igama le-API	Isalathiso	Inkcazo	USDMF	EU DMF	CEP
Captopril	Uxinzelelo lwegazi	USP/EP	√	√

Thumela i-imeyile kuthi

Iinkcukacha zeMveliso

Iithegi zeMveliso

IINKCUKACHA ZEMVELISO

Inkcazo

I-Captopril (SQ-14534) inamandla, inhibitor ekhuphisanayo ye-angiotensin-converting enzyme (ACE).

I-In vitro

I-Captopril (i-SQ-14534) ibonakaliswe ukuba inobungozi obufanayo kunye neenzuzo zokufa kulabo be-diuretics kunye ne-beta-blockers kwizigulane ezixinzelelekileyo.I-Captopril (i-SQ-14534) ibonakaliswe ukulibazisa ukuqhubela phambili kwe-nephropathy yesifo seswekile, kwaye i-enalapril kunye ne-lisinopril zithintela ukuphuhliswa kwe-nephropathy kwizigulane ze-normoalbuminuric ezinesifo seswekile[1].Umlinganiselo olinganayo we-cis kunye ne-trans States ye-Captopril (SQ-14534) ikhona kwisisombululo kwaye i-enzyme ikhetha kuphela i-trans state ye-inhibitor ebonisa ukuhambelana kwe-architectural kunye ne-stereoelectronic kunye ne-substrate ebophelelayo i-groove [2].

I-MCE ayizange iqinisekise ngokuzimeleyo ukuchaneka kwezi ndlela.Zenzelwe ireferensi kuphela.

Ulingo lwezonyango

Inombolo ye-NCT	Umxhasi	Imeko	Umhla wokuqala	Isigaba
NCT03179163	IYunivesithi yasePenn State\|Intliziyo yeSizwe, iLung, kunye neZiko leGazi (NHLBI)	Uxinzelelo lwegazi, kubalulekile	NgoJulayi 20, 2016	Isigaba 1\|Isigaba 2
NCT03660293	IYunivesithi yaseTanta	Isifo seswekile, uhlobo loku-1	Ngomhla woku-1 kuTshazimpuzi, ngo-2017	Ayingeni
NCT03147092	Centro Neurológico de Pesquisa e Reabiitação, eBrazil	Uxinzelelo lwegazi \| Uxinzelelo lwegazi	NgoFebruwari 1, 2018	Isigaba sokuqala soku-1
NCT00252317	IRigshospitalet, eDenmark	I-Aortic Stenosis	Novemba 2005	Inqanaba lesi-4
NCT02217852	Isibhedlele sase-West China	Uxinzelelo lwegazi	Agasti 2014	Inqanaba lesi-4
NCT01626469	Brigham kunye neSibhedlele sabaseTyhini	Uhlobo lwesi-2 seswekile iMellitus	Meyi 2012	Isigaba 1\|Isigaba 2
NCT00391846	AstraZeneca	Ukungaphumeleli kwentliziyo\|Ukungasebenzi kakuhle kwe-Venticular, eKhohlo	Okthobha 2006	Inqanaba lesi-4
NCT00240656	IYunivesithi yezoNyango yaseHebei	Uxinzelelo lwegazi, imiphunga	Okthobha 2005	Inqanaba loku-1
NCT00086723	IYunivesithi yaseNorthwestern\|Iziko leSizwe loMhlaza (NCI)	Ithumba eliqinileyo labadala elingachazwanga, iProtocol ecacileyo	Julayi 2003	Isigaba 1\|Isigaba 2
NCT00663949	IYunivesithi yaseShiraz yeSayensi yezoNyango	Isifo seswekile seNephropathy	NgoFebruwari 2006	Isigaba 2\|Isigaba 3
NCT01437371	Isibhedlele saseYunivesithi, eClermont-Ferrand\|Servier\|LivaNova	Ukumelwa yintliziyo	Agasti 2011	Inqanaba lesi-3
NCT04288700	KwiYunivesithi yaseAin Shams	Infantile Hemangioma	Nge-1 kaOkthobha, 2019	Inqanaba lesi-4
NCT00223717	IYunivesithi yaseVanderbilt \| Iziko lezoNyango leYunivesithi yaseVanderbilt	Uxinzelelo lwegazi	NgoJanuwari 2001	Inqanaba loku-1
NCT02770378	IYunivesithi yase-Ulm\|Unyango oluthembekileyo loMhlaza \| Ingxowa-mali ye-Anticancer, eBelgium	IGlioblastoma	EyeNkanga 2016	Isigaba 1\|Isigaba 2
NCT01761916	Instituto Materno Infantil Prof. Fernando Figueira	I-Preeclampsia	NgoJanuwari 2013	Inqanaba lesi-4
NCT01545479	Instituto de Cardiologia do Rio Grande do Sul	Isifo sezintso	NgoJanuwari 2010	Inqanaba lesi-4
NCT00935805	Hospital de Clinicas de Porto Alegre\|Conselho Nacional de Desenvolvimento Científico e Tecnológico\|Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul, Brazil	Isifo seswekile \| Uxinzelelo lwegazi	Julayi 2006
NCT00742040	Isibhedlele sabantwana abagulayo	Isifo sentliziyo	Agasti 2008	Inqanaba lesi-2
NCT03613506	IYunivesithi yaseWuhan	I-Radiotherapy Side Effect\|Ukuthatha iCaptopril	Ngo-Oktobha 25, 2018	Inqanaba lesi-2
NCT00004230	IYunivesithi yaseNorthwestern\|Iziko leSizwe loMhlaza (NCI)	Umhlaza	Okthobha 1999	Inqanaba lesi-3
NCT00660309	Novartis	Uhlobo lwesi-2 seswekile iMellitus	Epreli 2008	Inqanaba lesi-4
NCT00292162	I-NHS Greater Glasgow kunye neClyde	Ukungaphumeleli kweNtliziyo okuNgapheliyo \| UFibrillation yeAtrial	NgoJanuwari 2007	Ayingeni
NCT01271478	Coordinación de Investigación en Salud, Mexico	Ukukrala\|Isigaba sokuphela-Isifo sezintso	Agasti 2009	Inqanaba lesi-4
NCT04193137	IYunivesithi yezoNyango yaseChongqing	I-Aldosteronism yokuqala	NgoNovemba 30, 2019
NCT00155064	Isibhedlele seYunivesithi yeSizwe yaseTaiwan	Hyperaldosteronism	Julayi 2002	Inqanaba lesi-4
NCT01292694	IYunivesithi yaseVanderbilt \| Iziko lezoNyango leYunivesithi yaseVanderbilt	Uxinzelelo lwegazi \| Ukungaphumeleli okuNgenene okuZimelayo\|IAtrophy yeeNkqubo ezininzi	Matshi 2011	Inqanaba loku-1
NCT00917345	Isibhedlele seYunivesithi yeSizwe yaseTaiwan\|Novartis	I-Aldosteronism yokuqala	NgoJanuwari 2008
NCT00077064	IQela loNyango lweRadiation Oncology\|Iziko leSizwe loMhlaza (NCI)\|NRG Oncology	Umhlaza wemiphunga\|Iingxaki zemiphunga\|iRadiation Fibrosis	NgoJuni 2003	Inqanaba lesi-2