Doxycycline hyclate, eyaziwa ngokuba yi-doxycycline, iyeza elilwa ne-antibacterial lisetyenziswa rhoqo kuxilongo lwezonyango lwezilwanyana. Akukho mntu unokugweba ngokulula ukuba yeyiphi engcono phakathi kwayo kunye ne-fluphenazole.
Kwimarike yonyango lwezilwanyana, enye yezona antimicrobial ze-tetracycline zixhaphakile yi-doxycycline, elichiza eliqhelekileyo kumafama kunye noogqirha bezilwanyana abaphantsi. Nangona kunjalo, i-pharmacology kunye nokusetyenziswa kufuna iinzame zobungcali, ngoko awukwazi ukuyisebenzisa kakuhle ukuba uqhelene neli chiza kuphela. I-antibacterial mechanism ye-doxycycline kukuba ingena kakhulu kwiseli yebhaktheriya, idibanisa ne-ribosome 30S subunit target, i-organelle yeseli yebhakteria, ngaloo ndlela inqanda ukuhlanganiswa kweeprotheni zebhaktheriya, kwaye ivumela ukuba idlale umphumo osebenzayo we-antibacterial.
Zeziphi izifo ezinokunyangwa kusetyenziswa i-doxycycline?
I-Doxycycline isoloko isetyenziselwa unyango lwe-mycoplasma kwiinkukhu kunye nezifo zokuphefumla kwiihagu, ngakumbi kwizifo ezixubileyo ze-mycoplasma kunye neebhaktheriya.
● Izifo ezibangelwa ziintsholongwane
Kwizigulane ezine-pleuropneumonia, inyumoniya yehagu kunye nezinye izifo, banokusebenzisa i-doxycycline hydrochloride + fluphenazole + iziyobisi ze-antipyretic.
Kwi-actinomycetes enokubangela iipustules ezinokukhula kwiindawo ezahlukeneyo kwihagu, i-doxycycline hydrochloride iya kuhlala inesiphumo esingcono.
● Izifo zomzimba eziqhelekileyo
Kwi-mycoplasma, eyaziwa ngokuba yi-wheezing, i-doxycycline hydrochloride + flupenthixol ingasetyenziswa.
I-Spirochetes (igazi lehagu, njl.).
I-Doxycycline hydrochloride isebenza ngakumbi xa ilawulwa kwizifo ezifana ne-protozoa yegazi, esihlala sibhekisela kuyo njenge-epizootics.
Ii-antimicrobial ezine eziphambili ze-tetracycline
Kwimarike yezilwanyana zangoku, ii-antimicrobials ze-tetracycline eziphambili ziyi-doxycycline, i-tetracycline, i-oxytetracycline kunye ne-chlortetracycline, ezinomahluko omkhulu omnye komnye. Ukuba iyala ngokobuzwe, doxycycline> tetracycline> chlortetracycline> oxytetracycline. Ngaba uyazi ukuba kutheni uvakalelo lwe-chlortetracycline lusondele kwi-oxytetracycline? Enyanisweni, ngaphambi kokuba i-antibiotics ivalwe kwisondlo, i-chlortetracycline yayisetyenziselwa ukutya kwezilwanyana ngokubanzi, kwiidosi eziphantsi, imihla ngemihla kunye nexesha elide, njengokuba abantu badla kunye ne-MSG.
I-dose ephantsi, ebanzi, kunye nemihla ngemihla yokutya kwe-chlortetracycline iye yaphucula ukusebenza kwezilwanyana kwaye yakhuthaza uphuhliso olukhawulezayo nolunempilo lweshishini lokufama, nangona kunjalo, lizisa nesiphumo esibi kakhulu, oko kukuthi, idosi enjalo, indlela kunye neendlela zokulima ngokubanzi. uluhlu lokuchasa ibhaktheriya kuyo. Ngoko ke, xa olu hlobo lwechiza luvaliwe ukusetyenziswa kwisondlo, yinkqubela enkulu ekulawuleni ukusetyenziswa kwamachiza okulwa ne-antibacterial ukuguqula ichiza kwiyeza elimiselweyo ekufuneka linikwe ngugqirha wezilwanyana. Kuqikelelwa ukuba, emva kolu setyenziso lusemgangathweni, emva kwexesha elide lokubuyiselwa kwe-ecological, uvakalelo lwayo lunokubuyiselwa kwixesha elizayo.
Kutheni ibalulekile idoxycycline?
Doxycycline hyclate powder, enye ye-antibiotics ye-tetracycline ehamba phambili, sele ibalasele kwikliniki yezilwanyana iminyaka emininzi kangangokuba ibe yinto yesibini enkulu emva kwe-fluphenazole. Ukongeza, ngokumalunga nonyango lwemfuyo kunye nezifo zeenkukhu ekunzima ukucocwa ngexesha elifutshane, njenge-non-fever, ityuwa yomoya, i-influenza, kunye ne-mycoplasma bursa, njl., i-doxycycline ihlala idlala indima yayo. Indima eyodwa yonyango kunyango olusebenzayo lwezonyango zezi zifo zemfuyo kunye neenkukhu. Ngokuqhelekileyo, kunyango oluchazwe ngabagqirha bezilwanyana, kunye okanye ngaphandle kokuthatha inxaxheba kwe-doxycycline, umphumo ngamanye amaxesha ngumdlalo we-zero "osebenzayo" okanye "ongasebenziyo".
Imfuno yonyango lweklinikhi ye-doxycycline kwishishini lokufama liye landa kakhulu kwiminyaka embalwa edlulileyo ngenxa yokutshatyalaliswa kwe-bursitis, izifo ezinzima zokulawula ukuphefumula kunye ne-mycoplasma bursa. Ngokukodwa i-mycoplasma bursa, ngoku engeloxesha lonyaka konke konke, yenzeka rhoqo kwaye rhoqo unyaka wonke. Ke ngoko, abo banikela ingqalelo kwintengiso ye-doxycycline baya kufumanisa ukuba imfuno yentengiso ye-doxycycline ilahlekelwe lixesha layo lonyaka. Ngenxa yoko, naxa ilizwe lingene ngokubanzi kwihlobo elishushu, imfuno yemarike yedoxycycline ayipholanga ngenxa yobushushu obuphezulu.
I-antimicrobial spectrum yedoxycycline hyclateIvumela ukuba ifumane iziphumo zonyango ezigqwesileyo ngokuchasene ne-Gram-positive, i-Gram-negative, ibhaktiriya ye-aerobic kunye ne-anaerobic, kunye ne-rickettsia, i-spirochetes, i-mycoplasma, i-chlamydia kunye ne-protozoa, ebangela ukuba kutheni i-doxycycline yamkelwa ngamafama kunye noogqirha bezilwanyana ezininzi kangaka. iminyaka. Ngaphezu koko, amandla empembelelo ye-doxycycline kwi-Gram-positive ibhaktheriya ibhetele ngakumbi kunaleyo kwiibhaktheriya ze-Gram-negative, ngakumbi xa amaninzi amachiza angenalo uncedo kwi-Staphylococcus, umphumo we-doxycycline uhlala ukholisa.
Ngenxa yoko, phakathi kwe-tetracycline antimicrobials ekhoyo, i-doxycycline ayihambelani namanye amachiza okulwa neebhaktheriya eziqhelekileyo kwizifo zokuphefumula ezifana ne-Staphylococcus, i-Streptococcus pyogenes kunye ne-Pneumococcus, esinye sezizathu ezibaluleke kakhulu ukuba kutheni imimiselo emininzi yezilwanyana zonyango lwezifo zokuphefumula ziyakwazi. yahluke kakhulu okanye ngaphandle kokubandakanyeka kwe-doxycycline.
Amagalelo enziwe yi-CPF
I-CPF, i-pharmaceutical ehamba phambili kunyeumenzi we-doxycyclineye-APIs kunye nokwakhiwa okugqityiweyo e-China ufumanisa ukuba ngokwenene, abaphandi baselabhorethri, abanokukhetha ukuphonononga inyaniso malunga nesifo kunye nofuzo lokuxhathisa ichiza, banenjongo yokugqibela yokugqiba ithisisi okanye iphepha lophando. Le nkqubo yophononongo kunye nophando, nangona kunjalo, ihlala ithatha iinyanga okanye iminyaka, nto leyo ethatha ixesha elininzi kakhulu ukwenza isifo esifuna irejimeni yokuvula kwangoko ukulinda unyango. Ngoko ke, unyango olusebenzayo ngokweklinikhi luhlala lusekelwe kwidatha edlulileyo, ukuxilongwa kwentsimi kunye nokuxilongwa ngokukhawuleza kwelabhoratri, kwaye iingcebiso zonyango olusebenzayo zinikezelwa ngokukhawuleza.
Olu hlobo olukhawulezayo lwesigqibo sesifo esenziwe ngexesha elifutshane luya kubangela ngokulula abantu abaninzi abangaliqondiyo ichiza, ngakumbi abanako ngokuchanekileyo nangaphezulu umgwebo obanzi wosulelo lwentsholongwane ye-pathogenic ukubunjwa kwebhaktheriya ukuthatha ichiza ngobumfama kwaye isekelwe ekucingeni, ekwayindlela eyimfuneko apho abantu abaninzi kufuneka bathathe ukukhubeka kunye nokuqengqeleka ngaphambi kokuhlala beboleka koogqirha abadumileyo kwaye babe ngamayeza agqibeleleyo.
Ke ngoko, i-CPF izimisele ukutshintshiselana nawe ngolwazi lobugcisa olunxulumene neyeza lezilwanyana, i-pharmacology yezilwanyana, imimiselo yezilwanyana, imigaqo-nkqubo, ummiselo, ukuthengisa kunye nokusetyenziswa, ngenjongo yokufezekisa ukwabelana ngolwazi, ukuze abaphumeleleyo banyuke leleli iluncedo ukuya phezulu ukuze bafunde. into exabisekileyo.
Ixesha lokuposa: Aug-17-2022