Baloxavir Marboxil 1985606-14-1

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Baloxavir Marboxil 1985606-14-1 Umkhuhlane Shionogi kunye noRoche Sep.21,2031


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I-Baloxavir marboxil lichiza le-antiviral kwaye liyi-endonuclease inhibitor.Kwiimpuku kunye neenkawu, ukuxinwa kwegazi kweyeza kuphantsi kunomlinganiselo omncinci wokufumanisa kulawulo olulodwa lomlomo lwechiza.Kwimifuziselo yosulelo lwe-preclinical influenza A kunye no-B (kubandakanywa neentlobo ezixhathisayo kumachiza asele ekhona e-antiviral), i-Baloxavir marboxil inesiphumo esithile.

Iipropati zeMichiza

Ugcino Gcina kwi -20°C
M.Wt 571.55
Inombolo yeCas. 1985606-14-1
Ifomula I-C27H23F2N3O7S
Izithethantonye S-033188
Ukunyibilika Inyibilika kwi-DMSO
Igama leMchiza ((R)-12-((S)-7,8-difluoro-6,11-dihydrodibenzo[b,e]thiepin-11-yl)-6,8-dioxo-3,4,6,8, 12,12a-hexahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazin-7-yl)oxy)methyl methyl carbonate
SDF Khuphela iSDF
Uncumo lweCanonical O=C1C=CN(N([C@]2(N(C3=O)CCOC2)[H])[C@H]4C5=CC=C(C(F)=C5CSC6=CC=CC=C46) F)C3=C1OCOC(OC)=O
Imeko yokuthumela ngenqanawe Isisombululo sesampulu yovavanyo: inqanawa enomkhenkce oluhlaza.Zonke ezinye iisayizi ezikhoyo: inqanawa ene-RT, okanye umkhenkce oluhlaza xa uceliwe.
Iingcebiso ngokubanzi Ukufumana i-solubility ephezulu, nceda ufudumeze ityhubhu kwi-37 ° C kwaye uyigubungele kwindawo yokuhlamba i-ultrasonic ixesha elithile.Isisombululo sesitokhwe sinokugcinwa ngaphantsi kwe -20 ° C kwiinyanga ezininzi.

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Baloxavir-Marboxil-1985606-14-1

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2018 GMP-2
原料药GMP证书201811(captopril ,thalidomide etc)
GMP-of-PMDA-in-Chanyoo-平成28年08月03日 Nantong-Chanyoo-Pharmatech-Co
FDA-EIR-Letter-201901

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